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Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides

Isopeptide crosslinked proteins can be the product of transglutaminase or of exposure to organophosphorus toxicants (OP). Transglutaminase links glutamine to lysine with loss of ammonia. OP toxicants induce a link between glutamic acid and lysine with loss of water. Our goal was to establish criteri...

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Detalles Bibliográficos
Autores principales: Schopfer, Lawrence M., Onder, Seda, Lockridge, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270460/
https://www.ncbi.nlm.nih.gov/pubmed/34242352
http://dx.doi.org/10.1371/journal.pone.0254450