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Evaluation of mass spectrometry MS/MS spectra for the presence of isopeptide crosslinked peptides
Isopeptide crosslinked proteins can be the product of transglutaminase or of exposure to organophosphorus toxicants (OP). Transglutaminase links glutamine to lysine with loss of ammonia. OP toxicants induce a link between glutamic acid and lysine with loss of water. Our goal was to establish criteri...
Autores principales: | Schopfer, Lawrence M., Onder, Seda, Lockridge, Oksana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270460/ https://www.ncbi.nlm.nih.gov/pubmed/34242352 http://dx.doi.org/10.1371/journal.pone.0254450 |
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