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TGF-β1 Induces Immune Escape by Enhancing PD-1 and CTLA-4 Expression on T Lymphocytes in Hepatocellular Carcinoma

Primary liver cancer (PLC) is one of the most common types of cancer worldwide. Hepatocellular carcinoma (HCC) accounts for approximately 90% of PLC cases. The HCC microenvironment plays an important role in the occurrence and development of HCC. Immunotherapy for the HCC microenvironment has become...

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Detalles Bibliográficos
Autores principales: Bao, Shixiang, Jiang, Xiaopei, Jin, Shuai, Tu, Peipei, Lu, Jingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270637/
https://www.ncbi.nlm.nih.gov/pubmed/34249750
http://dx.doi.org/10.3389/fonc.2021.694145