Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells

How cells count and regulate organelle number is a fundamental question in cell biology. For example, most cells restrict centrioles to two in number and assemble one cilium; however, multiciliated cells (MCCs) synthesize hundreds of centrioles to assemble multiple cilia. Aberration in centriole/cil...

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Detalles Bibliográficos
Autores principales: Kulkarni, Saurabh, Marquez, Jonathan, Date, Priya, Ventrella, Rosa, Mitchell, Brian J, Khokha, Mustafa K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270640/
https://www.ncbi.nlm.nih.gov/pubmed/34184636
http://dx.doi.org/10.7554/eLife.66076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270640/
https://www.ncbi.nlm.nih.gov/pubmed/34184636
http://dx.doi.org/10.7554/eLife.66076

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