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Mechanical stretch scales centriole number to apical area via Piezo1 in multiciliated cells
How cells count and regulate organelle number is a fundamental question in cell biology. For example, most cells restrict centrioles to two in number and assemble one cilium; however, multiciliated cells (MCCs) synthesize hundreds of centrioles to assemble multiple cilia. Aberration in centriole/cil...
Autores principales: | Kulkarni, Saurabh, Marquez, Jonathan, Date, Priya, Ventrella, Rosa, Mitchell, Brian J, Khokha, Mustafa K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270640/ https://www.ncbi.nlm.nih.gov/pubmed/34184636 http://dx.doi.org/10.7554/eLife.66076 |
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