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Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice

Complement impacts innate and adaptive immunity. Using a model in which the human KEL glycoprotein is expressed on murine red blood cells (RBCs), we have shown that polyclonal immunoprophylaxis (KELIg) prevents alloimmunization to transfused RBCs when a recipient is in their baseline state of heath...

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Detalles Bibliográficos
Autores principales: Escamilla-Rivera, Vicente, Santhanakrishnan, Manjula, Liu, Jingchun, Gibb, David R., Forsmo, James E., Foxman, Ellen F., Eisenbarth, Stephanie C., Luckey, C. John, Zimring, James C., Hudson, Krystalyn E., Stowell, Sean R., Hendrickson, Jeanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270673/
https://www.ncbi.nlm.nih.gov/pubmed/34249009
http://dx.doi.org/10.3389/fimmu.2021.704072