Signaling of MK2 sustains robust AP1 activity for triple negative breast cancer tumorigenesis through direct phosphorylation of JAB1

Triple negative breast cancer (TNBC) cells are generally more invasive than estrogen receptor-positive (ER + ) breast cancer cells. Consistent with the importance of activator protein 1 (AP1) transcription factors in invasion, AP1 activity is much higher in TNBC lines than ER + lines. In TNBC cells,...

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Detalles Bibliográficos
Autores principales: Chen, Haoming, Padia, Ravi, Li, Tao, Li, Yue, Li, Bin, Jin, Lingtao, Huang, Shuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270897/
https://www.ncbi.nlm.nih.gov/pubmed/34244488
http://dx.doi.org/10.1038/s41523-021-00300-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270897/
https://www.ncbi.nlm.nih.gov/pubmed/34244488
http://dx.doi.org/10.1038/s41523-021-00300-1

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