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MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. However, there still remains a lack of effective diagnostic and therapeutic targets for this disease. Increasing evidence demonstrates that RNA modifications play an important role in the progression of HCC, but the rol...

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Detalles Bibliográficos
Autores principales: Xia, Peng, Zhang, Hao, Xu, Kequan, Jiang, Xiang, Gao, Meng, Wang, Ganggang, Liu, Yingyi, Yao, Ye, Chen, Xi, Ma, Weijie, Zhang, Zhonglin, Yuan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270967/
https://www.ncbi.nlm.nih.gov/pubmed/34244479
http://dx.doi.org/10.1038/s41419-021-03973-5