Cargando…

Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness

Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet to be clarified. We report in this study that the secretory ECM1a isoform induces tumorigenesis through the GPR motif binding to integrin αXβ2 and the activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Huijing, Wang, Jingshu, Li, Hui, Yu, Yinjue, Wang, Xiaoling, Lu, Lili, Lv, Cuiting, Chang, Bin, Jin, Wei, Guo, Wenwen, Ren, Chunxia, Yang, Gong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270969/ https://www.ncbi.nlm.nih.gov/pubmed/34244494 http://dx.doi.org/10.1038/s41467-021-24315-1

Ejemplares similares

Wentilactone A Reverses the NF-κB/ECM1 Signaling-Induced Cisplatin Resistance through Inhibition of IKK/IκB in Ovarian Cancer Cells
por: Lv, Cuiting, et al.
Publicado: (2022)

Profiling alternatively spliced mRNA isoforms for prostate cancer classification
por: Zhang, Chaolin, et al.
Publicado: (2006)

EASI—enrichment of alternatively spliced isoforms
por: Venables, Julian P., et al.
Publicado: (2006)

An alternatively spliced STING isoform localizes in the cytoplasmic membrane and directly senses extracellular cGAMP
por: Li, Xiaobo, et al.
Publicado: (2022)

Structures of alternatively spliced isoforms of human ketohexokinase
por: Trinh, Chi H., et al.
Publicado: (2009)

APPRIS: annotation of principal and alternative splice isoforms
por: Rodriguez, Jose Manuel, et al.
Publicado: (2013)

Alternative Splicing and Isoforms: From Mechanisms to Diseases
por: Liu, Qi, et al.
Publicado: (2022)

Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB
por: Khoo, Bernard, et al.
Publicado: (2007)

Differential Roles of Interleukin 15 mRNA Isoforms Generated by Alternative Splicing in Immune Responses in Vivo
por: Nishimura, Hitoshi, et al.
Publicado: (2000)

Evolution of the Plasma and Tissue Kallikreins, and Their Alternative Splicing Isoforms
por: Koumandou, Vassiliki Lila, et al.
Publicado: (2013)

Tau Isoforms: Gaining Insight into MAPT Alternative Splicing
por: Corsi, Andrea, et al.
Publicado: (2022)

Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2
por: MacNicol, Melanie C., et al.
Publicado: (2017)

Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
por: Berges, Natalia, et al.
Publicado: (2019)

Molecular Determinants and Specificity of mRNA with Alternatively-Spliced UPF1 Isoforms, Influenced by an Insertion in the ‘Regulatory Loop’
por: Padariya, Monikaben, et al.
Publicado: (2021)

Identification and functional comparison of novel alternatively spliced isoforms of human YAP
por: Liu, Lianlian, et al.
Publicado: (2023)

Alternative Splicing Isoforms of Porcine CREB Are Differentially Involved in Transcriptional Transactivation
por: Zhang, Dongjie, et al.
Publicado: (2022)

Alternative splicing results in RET isoforms with distinct trafficking properties
por: Richardson, Douglas S., et al.
Publicado: (2012)

Identification of alternatively spliced Dab1 and Fyn isoforms in pig
por: Long, Huan, et al.
Publicado: (2011)

A Novel CDX2 Isoform Regulates Alternative Splicing
por: Witek, Matthew E., et al.
Publicado: (2014)

The dynamic landscape of fission yeast meiosis alternative-splice isoforms
por: Kuang, Zheng, et al.
Publicado: (2017)

Systematic evaluation of isoform function in literature reports of alternative splicing
por: Bhuiyan, Shamsuddin A., et al.
Publicado: (2018)

Differential isoform expression and alternative splicing in sex determination in mice
por: Planells, Benjamín, et al.
Publicado: (2019)

Isoforms of Base Excision Repair Enzymes Produced by Alternative Splicing
por: Boldinova, Elizaveta O., et al.
Publicado: (2019)

Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
por: Lau, Edward, et al.
Publicado: (2019)

Alternative splicing is not a key source of chemerin isoforms diversity
por: Kwiecien, Kamila, et al.
Publicado: (2023)

Alternatively spliced isoforms of the human elk-1 mRNA within the 5′ UTR: implications for ELK-1 expression
por: Araud, Tanguy, et al.
Publicado: (2007)

Monoclonal antibodies in the analysis of fibronectin isoforms generated by alternative splicing of mRNA precursors in normal and transformed human cells
Publicado: (1987)

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells
por: Pickrell, Joseph K., et al.
Publicado: (2010)

The Alternatively Spliced Isoforms of Key Molecules in the cGAS-STING Signaling Pathway
por: Liang, Jiaqian, et al.
Publicado: (2021)

Alternatively Splicing Interactomes Identify Novel Isoform-Specific Partners for NSD2
por: Wang, Weidi, et al.
Publicado: (2021)

Alternative mRNA Splicing: Control by Combination
Publicado: (2005)

Alternative mRNA Splicing in the Pathogenesis of Obesity
por: Wong, Chi-Ming, et al.
Publicado: (2018)

Alternative splicing during Arabidopsis flower development results in constitutive and stage-regulated isoforms
por: Wang, Haifeng, et al.
Publicado: (2014)

Alternative Splicing of Arabidopsis IBR5 Pre-mRNA Generates Two IBR5 Isoforms with Distinct and Overlapping Functions
por: Jayaweera, Thilanka, et al.
Publicado: (2014)

Systematic Profiling of Alternative Splicing Events in Ovarian Cancer
por: Liu, Jia, et al.
Publicado: (2021)

CircAST: Full-length Assembly and Quantification of Alternatively Spliced Isoforms in Circular RNAs
por: Wu, Jing, et al.
Publicado: (2019)

SPACE: an algorithm to predict and quantify alternatively spliced isoforms using microarrays
por: Anton, Miguel A, et al.
Publicado: (2008)

Alternatively spliced isoforms encoded by cadherin genes from C. elegansgenome
por: Kashyap, Luv, et al.
Publicado: (2007)

Identification and Characterization of the Alternatively Spliced Nuclear Receptor Coactivator-6 Isoforms
por: Li, Qingtian, et al.
Publicado: (2011)

Estimation of alternative splicing isoform frequencies from RNA-Seq data
por: Nicolae, Marius, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_cde8bkdmc2bintusqd52ngo8n3