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Characterization of rifampicin-resistant Mycobacterium tuberculosis in Khyber Pakhtunkhwa, Pakistan

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is endemic in Pakistan. Resistance to both firstline rifampicin and isoniazid drugs (multidrug-resistant TB; MDR-TB) is hampering disease control. Rifampicin resistance is attributed to rpoB gene mutations, but rpoA and rpoC loci may also be i...

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Detalles Bibliográficos
Autores principales: Khan, Anwar Sheed, Phelan, Jody E., Khan, Muhammad Tahir, Ali, Sajid, Qasim, Muhammad, Napier, Gary, Campino, Susana, Ahmad, Sajjad, Cabral-Marques, Otavio, Zhang, Shulin, Rahman, Hazir, Wei, Dong-Qing, Clark, Taane G., Khan, Taj Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8270973/
https://www.ncbi.nlm.nih.gov/pubmed/34244539
http://dx.doi.org/10.1038/s41598-021-93501-4