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Sildenafil augments fetal weight and placental adiponectin in gestational testosterone-induced glucose intolerant rats

Testosterone induces intra-uterine growth restriction (IUGR) with maternal glucose dysregulation and oxidant release in various tissues. Adiponectin, which modulates the antioxidant nuclear factor erythroid 2-related factor 2 (Nrf2) signaling is expressed in the placenta and affects fetal growth. Si...

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Detalles Bibliográficos
Autores principales: Areola, Emmanuel Damilare, Adewuyi, Ifeoluwa Jesufemi, Usman, Taofeek Olumayowa, Tamunoibuomi, God’sgift, Arogundade, Lucy Kemi, Olaoye, Barakat, Matt-Ojo, Deborah Damilayo, Jeje, Abdulrazaq Olatunji, Oyabambi, Adewumi Oluwafemi, Afolayan, Enoch Abiodun, Olatunji, Lawrence Aderemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271103/
https://www.ncbi.nlm.nih.gov/pubmed/34277360
http://dx.doi.org/10.1016/j.toxrep.2021.06.011