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Sildenafil augments fetal weight and placental adiponectin in gestational testosterone-induced glucose intolerant rats
Testosterone induces intra-uterine growth restriction (IUGR) with maternal glucose dysregulation and oxidant release in various tissues. Adiponectin, which modulates the antioxidant nuclear factor erythroid 2-related factor 2 (Nrf2) signaling is expressed in the placenta and affects fetal growth. Si...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271103/ https://www.ncbi.nlm.nih.gov/pubmed/34277360 http://dx.doi.org/10.1016/j.toxrep.2021.06.011 |