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Co-evolutionary landscape at the interface and non-interface regions of protein-protein interaction complexes
Proteins involved in interactions throughout the course of evolution tend to co-evolve and compensatory changes may occur in interacting proteins to maintain or refine such interactions. However, certain residue pair alterations may prove to be detrimental for functional interactions. Hence, determi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271121/ https://www.ncbi.nlm.nih.gov/pubmed/34285778 http://dx.doi.org/10.1016/j.csbj.2021.06.039 |