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Co-evolutionary landscape at the interface and non-interface regions of protein-protein interaction complexes

Proteins involved in interactions throughout the course of evolution tend to co-evolve and compensatory changes may occur in interacting proteins to maintain or refine such interactions. However, certain residue pair alterations may prove to be detrimental for functional interactions. Hence, determi...

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Detalles Bibliográficos
Autores principales: Mukherjee, Ishita, Chakrabarti, Saikat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271121/
https://www.ncbi.nlm.nih.gov/pubmed/34285778
http://dx.doi.org/10.1016/j.csbj.2021.06.039