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Assays for studying normal versus suppressive ERAD-associated retrotranslocation pathways in yeast
In S. cerevisiae, we identified rhomboid pseudoprotease Dfm1 as the major mediator for removing or retrotranslocating misfolded membrane substrates from the ER (endoplasmic reticulum). Long-standing challenges with rapid suppression of dfm1-null cells have limited the biochemical study of Dfm1’s rol...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271171/ https://www.ncbi.nlm.nih.gov/pubmed/34278330 http://dx.doi.org/10.1016/j.xpro.2021.100640 |