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Assays for studying normal versus suppressive ERAD-associated retrotranslocation pathways in yeast

In S. cerevisiae, we identified rhomboid pseudoprotease Dfm1 as the major mediator for removing or retrotranslocating misfolded membrane substrates from the ER (endoplasmic reticulum). Long-standing challenges with rapid suppression of dfm1-null cells have limited the biochemical study of Dfm1’s rol...

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Detalles Bibliográficos
Autores principales: Bhaduri, Satarupa, Neal, Sonya E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271171/
https://www.ncbi.nlm.nih.gov/pubmed/34278330
http://dx.doi.org/10.1016/j.xpro.2021.100640