The small Cajal body-specific RNA 15 (SCARNA15) directs p53 and redox homeostasis via selective splicing in cancer cells

Small Cajal body-specific RNAs (scaRNAs) guide post-transcriptional modification of spliceosomal RNA and, while commonly altered in cancer, have poorly defined roles in tumorigenesis. Here, we uncover that SCARNA15 directs alternative splicing (AS) and stress adaptation in cancer cells. Specifically...

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Detalles Bibliográficos
Autores principales: Beneventi, Giulia, Munita, Roberto, Cao Thi Ngoc, Phuong, Madej, Magdalena, Cieśla, Maciej, Muthukumar, Sowndarya, Krogh, Nicolai, Nielsen, Henrik, Swaminathan, Vinay, Bellodi, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Cancer-specific RNAs and RNA Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271217/
https://www.ncbi.nlm.nih.gov/pubmed/34316713
http://dx.doi.org/10.1093/narcan/zcab026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271217/
https://www.ncbi.nlm.nih.gov/pubmed/34316713
http://dx.doi.org/10.1093/narcan/zcab026

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