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Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking

Herein, we present the synthesis and crystal structures determination of five 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives containing halogen atoms, 6a–e, which may be used as an excellent mimic of steroids in the drug development process. Good quality crystals obtained for all of the synthe...

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Detalles Bibliográficos
Autores principales: Daśko, Mateusz, Dołęga, Anna, Siedzielnik, Magdalena, Biernacki, Karol, Ciupak, Olga, Rachon, Janusz, Demkowicz, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271369/
https://www.ncbi.nlm.nih.gov/pubmed/34279404
http://dx.doi.org/10.3390/molecules26134059