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Novel 1,2,3-Triazole Derivatives as Mimics of Steroidal System—Synthesis, Crystal Structures Determination, Hirshfeld Surfaces Analysis and Molecular Docking
Herein, we present the synthesis and crystal structures determination of five 4-(1-phenyl-1H-1,2,3-triazol-4-yl)phenol derivatives containing halogen atoms, 6a–e, which may be used as an excellent mimic of steroids in the drug development process. Good quality crystals obtained for all of the synthe...
Autores principales: | Daśko, Mateusz, Dołęga, Anna, Siedzielnik, Magdalena, Biernacki, Karol, Ciupak, Olga, Rachon, Janusz, Demkowicz, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271369/ https://www.ncbi.nlm.nih.gov/pubmed/34279404 http://dx.doi.org/10.3390/molecules26134059 |
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