Design, Synthesis and Biological Evaluation of Novel Pyrazolo[1,2,4]triazolopyrimidine Derivatives as Potential Anticancer Agents

Three novel pyrazolo-[4,3-e][1,2,4]triazolopyrimidine derivatives (1, 2, and 3) were designed, synthesized, and evaluated for their in vitro biological activity. All three compounds exhibited different levels of cytotoxicity against cervical and breast cancer cell lines. However, compound 1 showed t...

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Detalles Bibliográficos
Autores principales: Aliwaini, Saeb, Abu Thaher, Bassam, Al-Masri, Ihab, Shurrab, Nabil, El-Kurdi, Said, Schollmeyer, Dieter, Qeshta, Basem, Ghunaim, Mariam, Csuk, René, Laufer, Stefan, Kaiser, Lars, Deigner, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271544/
https://www.ncbi.nlm.nih.gov/pubmed/34279406
http://dx.doi.org/10.3390/molecules26134065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271544/
https://www.ncbi.nlm.nih.gov/pubmed/34279406
http://dx.doi.org/10.3390/molecules26134065

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