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Alternative splicing of GluN1 gates glycine site–dependent nonionotropic signaling by NMDAR receptors

N-methyl-D-aspartate (NMDA) receptors (NMDARs), a principal subtype of excitatory neurotransmitter receptor, are composed as tetrameric assemblies of two glycine-binding GluN1 subunits and two glutamate-binding GluN2 subunits. NMDARs can signal nonionotropically through binding of glycine alone to i...

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Detalles Bibliográficos
Autores principales: Li, Hongbin, Rajani, Vishaal, Han, Lu, Chung, Danielle, Cooke, James E., Sengar, Ameet S., Salter, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271567/
https://www.ncbi.nlm.nih.gov/pubmed/34187890
http://dx.doi.org/10.1073/pnas.2026411118