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Alternative splicing of GluN1 gates glycine site–dependent nonionotropic signaling by NMDAR receptors
N-methyl-D-aspartate (NMDA) receptors (NMDARs), a principal subtype of excitatory neurotransmitter receptor, are composed as tetrameric assemblies of two glycine-binding GluN1 subunits and two glutamate-binding GluN2 subunits. NMDARs can signal nonionotropically through binding of glycine alone to i...
Autores principales: | Li, Hongbin, Rajani, Vishaal, Han, Lu, Chung, Danielle, Cooke, James E., Sengar, Ameet S., Salter, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271567/ https://www.ncbi.nlm.nih.gov/pubmed/34187890 http://dx.doi.org/10.1073/pnas.2026411118 |
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