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Efficacy of a Covalent Microtubule Stabilizer in Taxane-Resistant Ovarian Cancer Models
Ovarian cancer often has a poor clinical prognosis because of late detection, frequently after metastatic progression, as well as acquired resistance to taxane-based therapy. Herein, we evaluate a novel class of covalent microtubule stabilizers, the C-22,23-epoxytaccalonolides, for their efficacy ag...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8271594/ https://www.ncbi.nlm.nih.gov/pubmed/34279417 http://dx.doi.org/10.3390/molecules26134077 |