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5-Phenoxy Primaquine Analogs and the Tetraoxane Hybrid as Antimalarial Agents

The rapid emergence of drug resistance to the current antimalarial agents has led to the urgent need for the discovery of new and effective compounds. In this work, a series of 5-phenoxy primaquine analogs with 8-aminoquinoline core (7a–7h) was synthesized and investigated for their antimalarial act...

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Detalles Bibliográficos
Autores principales: Jansongsaeng, Somruedee, Srimongkolpithak, Nitipol, Pengon, Jutharat, Kamchonwongpaisan, Sumalee, Khotavivattana, Tanatorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272044/
https://www.ncbi.nlm.nih.gov/pubmed/34208832
http://dx.doi.org/10.3390/molecules26133991