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Novel Bradykinin Receptor Inhibitors Inhibit Proliferation and Promote the Apoptosis of Hepatocellular Carcinoma Cells by Inhibiting the ERK Pathway

Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Studies have shown that bradykinin (BK) is highly expressed in liver cancer. We designed the novel BK receptor inhibitors J051-71 and J051-105, which reduced the viability of liver cancer cells and inhibited the formation of c...

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Detalles Bibliográficos
Autores principales: Wang, Yiou, Zhang, Bingxue, Huang, Yibing, Yao, Wenjun, Tao, Fei, Chen, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272207/
https://www.ncbi.nlm.nih.gov/pubmed/34206871
http://dx.doi.org/10.3390/molecules26133915