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Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development
Despite the advances in intensive chemotherapy regimens and targeted therapies, overall survival (OS) of acute myeloid leukemia (AML) remains unfavorable due to inevitable chemotherapy resistance and high relapse rate, which mainly caused by the persistence existence of leukemia stem cells (LSCs). B...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272391/ https://www.ncbi.nlm.nih.gov/pubmed/34246314 http://dx.doi.org/10.1186/s40164-021-00233-2 |