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Leukemia stem cell-bone marrow microenvironment interplay in acute myeloid leukemia development

Despite the advances in intensive chemotherapy regimens and targeted therapies, overall survival (OS) of acute myeloid leukemia (AML) remains unfavorable due to inevitable chemotherapy resistance and high relapse rate, which mainly caused by the persistence existence of leukemia stem cells (LSCs). B...

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Detalles Bibliográficos
Autores principales: Yao, Yiyi, Li, Fenglin, Huang, Jiansong, Jin, Jie, Wang, Huafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272391/
https://www.ncbi.nlm.nih.gov/pubmed/34246314
http://dx.doi.org/10.1186/s40164-021-00233-2