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Probing the signaling requirements for naive human pluripotency by high-throughput chemical screening

Naive human embryonic stem cells (hESCs) have been isolated that more closely resemble the pre-implantation epiblast compared to conventional “primed” hESCs, but the signaling principles underlying these discrete stem cell states remain incompletely understood. Here, we describe the results from a h...

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Detalles Bibliográficos
Autores principales: Khan, Shafqat A., Park, Kyoung-mi, Fischer, Laura A., Dong, Chen, Lungjangwa, Tenzin, Jimenez, Marta, Casalena, Dominick, Chew, Brian, Dietmann, Sabine, Auld, Douglas S., Jaenisch, Rudolf, Theunissen, Thorold W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272458/
https://www.ncbi.nlm.nih.gov/pubmed/34133938
http://dx.doi.org/10.1016/j.celrep.2021.109233