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Hydroxyphenyl Butanone Induces Cell Cycle Arrest through Inhibition of GSK3β in Colorectal Cancer

BACKGROUND: Colorectal cancer (CRC) is among the top three gastrointestinal malignancy in morbidity and mortality. The abnormal activation of Wnt/β-catenin pathway is considered to be a key factor in the occurrence and development of CRC. Novel inhibitor discovery against key factor in WNT pathway i...

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Detalles Bibliográficos
Autores principales: Zhang, Songyan, Wang, Yunfeng, Zhang, Haopeng, Sun, Chengming, Dang, Shuwei, Liu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272657/
https://www.ncbi.nlm.nih.gov/pubmed/34307685
http://dx.doi.org/10.1155/2021/9981815