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Chronic unpredictable stress induces depression-related behaviors by suppressing AgRP neuron activity

Previous studies have shown that AgRP neurons in the arcuate nucleus (ARC) respond to energy deficits and play a key role in the control of feeding behavior and metabolism. Here, we demonstrate that chronic unpredictable stress, an animal model of depression, decreases spontaneous firing rates, incr...

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Detalles Bibliográficos
Autores principales: Fang, Xing, Jiang, Shujun, Wang, Jiangong, Bai, Yu, Kim, Chung Sub, Blake, David, Weintraub, Neal L., Lei, Yun, Lu, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272726/
https://www.ncbi.nlm.nih.gov/pubmed/33432188
http://dx.doi.org/10.1038/s41380-020-01004-x