DNA methylation analysis reveals epimutation hotspots in patients with dilated cardiomyopathy-associated laminopathies

BACKGROUND: Mutations in LMNA, encoding lamin A/C, lead to a variety of diseases known as laminopathies including dilated cardiomyopathy (DCM) and skeletal abnormalities. Though previous studies have investigated the dysregulation of gene expression in cells from patients with DCM, the role of epige...

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Detalles Bibliográficos
Autores principales: Morival, Julien L. P., Widyastuti, Halida P., Nguyen, Cecilia H. H., Zaragoza, Michael V., Downing, Timothy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272901/
https://www.ncbi.nlm.nih.gov/pubmed/34246298
http://dx.doi.org/10.1186/s13148-021-01127-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8272901/
https://www.ncbi.nlm.nih.gov/pubmed/34246298
http://dx.doi.org/10.1186/s13148-021-01127-0

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