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A Phase 1 study Combining Pexidartinib, Radiation Therapy, and Androgen Deprivation Therapy in Men With Intermediate- and High-Risk Prostate Cancer

PURPOSE: This study aimed to evaluate a combination of radiation therapy (RT), androgen deprivation therapy (ADT), and pexidartinib (colony-stimulating factor 1 receptor [CSF1R]) inhibitor in men with intermediate- and high-risk prostate cancer. CSF1R signaling promotes tumor infiltration and surviv...

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Detalles Bibliográficos
Autores principales: Hamid, Muhammad, Heilbrun, Lance K., Maier, Jordan, Devisetty, Kiran, Connolly, Irene, Kaufman, Isaac, Dobson, Kimberlee, Herroon, Mackenzie K., Smith, Daryn, Sampson, Sandra, Podgorski, Izabela, Heath, Elisabeth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273039/
https://www.ncbi.nlm.nih.gov/pubmed/34286163
http://dx.doi.org/10.1016/j.adro.2021.100679