PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway

A growing amount of evidence has confirmed the crucial role of the prolyl isomerase PIN1 in aging and age-related diseases. However, the mechanism of PIN1 in age-related hearing loss (ARHL) remains unclear. Pathologically, ARHL is primarily due to the loss and dysfunction of hair cells (HCs) and spi...

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Detalles Bibliográficos
Autores principales: Zhang, Yanzhuo, Lv, Zhe, Liu, Yudong, Cao, Huan, Yang, Jianwang, Wang, Baoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273041/
https://www.ncbi.nlm.nih.gov/pubmed/34285767
http://dx.doi.org/10.1155/2021/9980444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273041/
https://www.ncbi.nlm.nih.gov/pubmed/34285767
http://dx.doi.org/10.1155/2021/9980444

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