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Etoposide, an anticancer drug involved in therapy-related secondary leukemia: Enzymes at play
Etoposide is a semi-synthetic glycoside derivative of podophyllotoxin, also known as VP-16. It is a widely used anticancer medicine in clinics. Unfortunately, high doses or long-term etoposide treatment can induce therapy-related leukemia. The mechanism by which etoposide induces secondary hematopoi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273223/ https://www.ncbi.nlm.nih.gov/pubmed/34243013 http://dx.doi.org/10.1016/j.tranon.2021.101169 |