Building predictive signaling models by perturbing yeast cells with time-varying stimulations resulting in distinct signaling responses

This protocol provides a step-by-step approach to perturb single cells with time-varying stimulation profiles, collect distinct signaling responses, and use these to infer a system of ordinary differential equations to capture and predict dynamics of protein-protein regulation in signal transduction...

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Detalles Bibliográficos
Autores principales: Jashnsaz, Hossein, Fox, Zachary R., Munsky, Brian, Neuert, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273411/
https://www.ncbi.nlm.nih.gov/pubmed/34286292
http://dx.doi.org/10.1016/j.xpro.2021.100660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273411/
https://www.ncbi.nlm.nih.gov/pubmed/34286292
http://dx.doi.org/10.1016/j.xpro.2021.100660

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