Programmed PPAR-α downregulation induces inflammaging by suppressing fatty acid catabolism in monocytes

Inflammaging is associated with an increased risk of chronic disease. Monocytes are the principal immune cells for the production of inflammatory cytokines and contribute to inflammaging in the elderly. However, the underlying mechanisms remain largely unknown. Here, we found that monocytes from age...

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Detalles Bibliográficos
Autores principales: Wang, Ming, Yan, Yan, Zhang, Zhengguo, Yao, Xiaohan, Duan, Xixi, Jiang, Ziming, An, Junfeng, Zheng, Peiguo, Han, Yijie, Wu, Hao, Wang, Zhaoqing, Glauben, Rainer, Qin, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273418/
https://www.ncbi.nlm.nih.gov/pubmed/34286232
http://dx.doi.org/10.1016/j.isci.2021.102766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273418/
https://www.ncbi.nlm.nih.gov/pubmed/34286232
http://dx.doi.org/10.1016/j.isci.2021.102766

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