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Loss of Claudin-3 Impairs Hepatic Metabolism, Biliary Barrier Function, and Cell Proliferation in the Murine Liver

BACKGROUND & AIMS: Tight junctions in the liver are essential to maintain the blood-biliary barrier, however, the functional contribution of individual tight junction proteins to barrier and metabolic homeostasis remains largely unexplored. Here, we describe the cell type–specific expression of...

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Detalles Bibliográficos
Autores principales: Baier, Felix Alexander, Sánchez-Taltavull, Daniel, Yarahmadov, Tural, Castellà, Cristina Gómez, Jebbawi, Fadi, Keogh, Adrian, Tombolini, Riccardo, Odriozola, Adolfo, Dias, Mariana Castro, Deutsch, Urban, Furuse, Mikio, Engelhardt, Britta, Zuber, Benoît, Odermatt, Alex, Candinas, Daniel, Stroka, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273426/
https://www.ncbi.nlm.nih.gov/pubmed/33866021
http://dx.doi.org/10.1016/j.jcmgh.2021.04.003