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Genome-Wide DNA Methylation Changes Associated With High-Altitude Acclimatization During an Everest Base Camp Trek

The individual physiological response to high-altitude hypoxia involves both genetic and non-genetic factors, including epigenetic modifications. Epigenetic changes in hypoxia factor pathway (HIF) genes are associated with high-altitude acclimatization. However, genome-wide epigenetic changes that a...

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Detalles Bibliográficos
Autores principales: Childebayeva, Ainash, Harman, Taylor, Weinstein, Julien, Day, Trevor, Brutsaert, Tom D., Bigham, Abigail W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273439/
https://www.ncbi.nlm.nih.gov/pubmed/34262470
http://dx.doi.org/10.3389/fphys.2021.660906