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PDGF-D activation by macrophage-derived uPA promotes AngII-induced cardiac remodeling in obese mice
Obesity-induced secretory disorder of adipose tissue–derived factors is important for cardiac damage. However, whether platelet-derived growth factor-D (PDGF-D), a newly identified adipokine, regulates cardiac remodeling in angiotensin II (AngII)–infused obese mice is unclear. Here, we found obesity...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273546/ https://www.ncbi.nlm.nih.gov/pubmed/34236404 http://dx.doi.org/10.1084/jem.20210252 |