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Tumor Microenvironment Alters Chemoresistance of Hepatocellular Carcinoma Through CYP3A4 Metabolic Activity

Variations in tumor biology from patient to patient combined with the low overall survival rate of hepatocellular carcinoma (HCC) present significant clinical challenges. During the progression of chronic liver diseases from inflammation to the development of HCC, microenvironmental properties, incl...

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Detalles Bibliográficos
Autores principales: Özkan, Alican, Stolley, Danielle L., Cressman, Erik N. K., McMillin, Matthew, DeMorrow, Sharon, Yankeelov, Thomas E., Rylander, Marissa Nichole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273608/
https://www.ncbi.nlm.nih.gov/pubmed/34262860
http://dx.doi.org/10.3389/fonc.2021.662135