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Tumor Microenvironment Alters Chemoresistance of Hepatocellular Carcinoma Through CYP3A4 Metabolic Activity
Variations in tumor biology from patient to patient combined with the low overall survival rate of hepatocellular carcinoma (HCC) present significant clinical challenges. During the progression of chronic liver diseases from inflammation to the development of HCC, microenvironmental properties, incl...
Autores principales: | Özkan, Alican, Stolley, Danielle L., Cressman, Erik N. K., McMillin, Matthew, DeMorrow, Sharon, Yankeelov, Thomas E., Rylander, Marissa Nichole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273608/ https://www.ncbi.nlm.nih.gov/pubmed/34262860 http://dx.doi.org/10.3389/fonc.2021.662135 |
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