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Colombian Scorpion Centruroides margaritatus: Purification and Characterization of a Gamma Potassium Toxin with Full-Block Activity on the hERG1 Channel

The Colombian scorpion Centruroides margaritatus produces a venom considered of low toxicity. Nevertheless, there are known cases of envenomation resulting in cardiovascular disorders, probably due to venom components that target ion channels. Among them, the human ether-à-go-go-Related gene (hERG1)...

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Detalles Bibliográficos
Autores principales: Beltrán-Vidal, José, Carcamo-Noriega, Edson, Pastor, Nina, Zamudio-Zuñiga, Fernando, Guerrero-Vargas, Jimmy Alexander, Castaño, Santiago, Possani, Lourival Domingos, Restano-Cassulini, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273696/
https://www.ncbi.nlm.nih.gov/pubmed/34201318
http://dx.doi.org/10.3390/toxins13060407