Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins

The ancient paralogs premelanosome protein (PMEL) and glycoprotein nonmetastatic melanoma protein B (GPNMB) have independently emerged as intriguing disease loci in recent years. Both proteins possess common functional domains and variants that cause a shared spectrum of overlapping phenotypes and d...

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Detalles Bibliográficos
Autores principales: Chrystal, Paul W., Footz, Tim, Hodges, Elizabeth D., Jensen, Justin A., Walter, Michael A., Allison, W. Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273697/
https://www.ncbi.nlm.nih.gov/pubmed/34207849
http://dx.doi.org/10.3390/molecules26123529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273697/
https://www.ncbi.nlm.nih.gov/pubmed/34207849
http://dx.doi.org/10.3390/molecules26123529

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