An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum

Neuroligin is a postsynaptic cell-adhesion molecule that is involved in synapse formation and maturation by interacting with presynaptic neurexin. Mutations in neuroligin genes, including the arginine to cystein substitution at the 451st amino acid residue (R451C) of neuroligin-3 (NLGN3), have been...

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Detalles Bibliográficos
Autores principales: Lai, Esther Suk King, Nakayama, Hisako, Miyazaki, Taisuke, Nakazawa, Takanobu, Tabuchi, Katsuhiko, Hashimoto, Kouichi, Watanabe, Masahiko, Kano, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273702/
https://www.ncbi.nlm.nih.gov/pubmed/34262438
http://dx.doi.org/10.3389/fncir.2021.676891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273702/
https://www.ncbi.nlm.nih.gov/pubmed/34262438
http://dx.doi.org/10.3389/fncir.2021.676891

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