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An Autism-Associated Neuroligin-3 Mutation Affects Developmental Synapse Elimination in the Cerebellum
Neuroligin is a postsynaptic cell-adhesion molecule that is involved in synapse formation and maturation by interacting with presynaptic neurexin. Mutations in neuroligin genes, including the arginine to cystein substitution at the 451st amino acid residue (R451C) of neuroligin-3 (NLGN3), have been...
Autores principales: | Lai, Esther Suk King, Nakayama, Hisako, Miyazaki, Taisuke, Nakazawa, Takanobu, Tabuchi, Katsuhiko, Hashimoto, Kouichi, Watanabe, Masahiko, Kano, Masanobu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273702/ https://www.ncbi.nlm.nih.gov/pubmed/34262438 http://dx.doi.org/10.3389/fncir.2021.676891 |
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