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Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease

BACKGROUND/AIMS: Acute kidney injury (AKI) is an underestimated yet important risk factor for the development of chronic kidney disease (CKD), characterized by tubulointerstitial fibrosis and tubular dedifferentiation. Tubular dedifferentiation, which is associated with the loss of epithelial marker...

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Detalles Bibliográficos
Autores principales: Kim, Il Young, Park, Yeon Kyeong, Song, Sang Heon, Seong, Eun Young, Lee, Dong Won, Bae, Sun Sik, Lee, Soo Bong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Internal Medicine 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273823/
https://www.ncbi.nlm.nih.gov/pubmed/33322851
http://dx.doi.org/10.3904/kjim.2020.198