Design of a Stable Cyclic Peptide Analgesic Derived from Sunflower Seeds that Targets the κ-Opioid Receptor for the Treatment of Chronic Abdominal Pain

[Image: see text] The rising opioid crisis has become a worldwide societal and public health burden, resulting from the abuse of prescription opioids. Targeting the κ-opioid receptor (KOR) in the periphery has emerged as a powerful approach to develop novel pain medications without central side effe...

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Detalles Bibliográficos
Autores principales: Muratspahić, Edin, Tomašević, Nataša, Koehbach, Johannes, Duerrauer, Leopold, Hadžić, Seid, Castro, Joel, Schober, Gudrun, Sideromenos, Spyridon, Clark, Richard J., Brierley, Stuart M., Craik, David J., Gruber, Christian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273886/
https://www.ncbi.nlm.nih.gov/pubmed/34162205
http://dx.doi.org/10.1021/acs.jmedchem.1c00158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273886/
https://www.ncbi.nlm.nih.gov/pubmed/34162205
http://dx.doi.org/10.1021/acs.jmedchem.1c00158

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