Heterogeneous antiretroviral drug distribution and HIV/SHIV detection in the gut of three species

HIV replication within tissues may increase in response to a reduced exposure to antiretroviral drugs. Traditional approaches to measuring drug concentrations in tissues are unable to characterize a heterogeneous drug distribution. Here, we used mass spectrometry imaging (MSI) to visualize the distr...

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Detalles Bibliográficos
Autores principales: Thompson, Corbin G., Rosen, Elias P., Prince, Heather M. A., White, Nicole, Sykes, Craig, de la Cruz, Gabriela, Mathews, Michelle, Deleage, Claire, Estes, Jacob D., Charlins, Paige, Mulder, Leila R., Kovarova, Martina, Adamson, Lourdes, Arora, Shifali, Dellon, Evan S., Peery, Anne F., Shaheen, Nicholas J., Gay, Cynthia, Muddiman, David C., Akkina, Ramesh, Garcia, J. Victor, Luciw, Paul, Kashuba, Angela D. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273920/
https://www.ncbi.nlm.nih.gov/pubmed/31270274
http://dx.doi.org/10.1126/scitranslmed.aap8758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273920/
https://www.ncbi.nlm.nih.gov/pubmed/31270274
http://dx.doi.org/10.1126/scitranslmed.aap8758

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