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Downregulation of NKG2DLs by TGF-β in human lung cancer cells

BACKGROUND: Transforming growth factor beta (TGF-β) is a typical immuno-inhibitory cytokine and highly secreted by lung cancer cells. It was supposed that its immunosuppressive effects to NK cell might be related with the altered expression of activating and inhibitory molecules in lung cancer cells...

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Detalles Bibliográficos
Autores principales: Lee, Young Shin, Choi, Hojung, Cho, Hae-Ryung, Son, Woo-Chang, Park, You-Soo, Kang, Chi-Dug, Bae, Jaeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273967/
https://www.ncbi.nlm.nih.gov/pubmed/34253166
http://dx.doi.org/10.1186/s12865-021-00434-8