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Augmented peroxisomal ROS buffering capacity renders oxidative and thermal stress cross-tolerance in yeast

BACKGROUND: Thermotolerant yeast has outstanding potential in industrial applications. Komagataella phaffii (Pichia pastoris) is a common cell factory for industrial production of heterologous proteins. RESULTS: Herein, we obtained a thermotolerant K. phaffii mutant G14 by mutagenesis and adaptive e...

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Detalles Bibliográficos
Autores principales: Lin, Nai-Xin, He, Rui-Zhen, Xu, Yan, Yu, Xiao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273976/
https://www.ncbi.nlm.nih.gov/pubmed/34247591
http://dx.doi.org/10.1186/s12934-021-01623-1