The germline/somatic DNA damage repair gene mutations modulate the therapeutic response in Chinese patients with advanced pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with molecular heterogeneity, inducing differences in biological behavior, and therapeutic strategy. NGS profiles of pathogenic alterations in the Chinese PDAC population are limited. We conducted a retrospective study to investi...

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Detalles Bibliográficos
Autores principales: Shui, Lin, Li, Xiaofen, Peng, Yang, Tian, Jiangfang, Li, Shuangshuang, He, Du, Li, Ang, Tian, Bole, Li, Mao, Gao, Heli, An, Ning, Yi, Cheng, Cao, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273977/
https://www.ncbi.nlm.nih.gov/pubmed/34247626
http://dx.doi.org/10.1186/s12967-021-02972-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273977/
https://www.ncbi.nlm.nih.gov/pubmed/34247626
http://dx.doi.org/10.1186/s12967-021-02972-6

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