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The potential oncogenic and MLN4924-resistant effects of CSN5 on cervical cancer cells

BACKGROUND: CSN5, a member of Cop9 signalosome, is essential for protein neddylation. It has been supposed to serve as an oncogene in some cancers. However, the role of CSN5 has not been investigated in cervical cancer yet. METHODS: Data from TCGA cohorts and GEO dataset was analyzed to examine the...

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Detalles Bibliográficos
Autores principales: Zhang, Huilin, He, Ping, Zhou, Qing, Lu, Yan, Lu, Bingjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8273998/
https://www.ncbi.nlm.nih.gov/pubmed/34247597
http://dx.doi.org/10.1186/s12935-021-02078-5