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Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis

Sepsis is a complex syndrome related to an infection‐induced exaggerated inflammatory response, which is associated with a high mortality. Granzymes (Gzm) are proteases mainly found in cytotoxic lymphocytes that not only have a role in target cell death, but also as mediators of infection and inflam...

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Detalles Bibliográficos
Autores principales: García‐Laorden, M. Isabel, Hoogendijk, Arie J., Wiewel, Maryse A., van Vught, Lonneke A., Schultz, Marcus J., Bovenschen, Niels, de Vos, Alex F., van der Poll, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274148/
https://www.ncbi.nlm.nih.gov/pubmed/33866542
http://dx.doi.org/10.1111/cei.13601