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Modeling the population effects of escape mutations in SARS-CoV-2 to guide vaccination strategies

SARS-Cov-2 escape mutations (EM) have been detected and are spreading. Vaccines may need adjustment to respond to these or future mutations. We designed a population level model integrating both waning immunity and EM. We also designed a set of criteria for elaborating and fitting this model to cros...

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Detalles Bibliográficos
Autores principales: Koopman, James S., Simon, Carl P., Getz, Wayne M., Salter, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274275/
https://www.ncbi.nlm.nih.gov/pubmed/34375814
http://dx.doi.org/10.1016/j.epidem.2021.100484